To stabilize the state at elevated pressure, they take both drugs Amlodipine and Lorista. The drugs have high compatibility. Combination therapy allows you to achieve a rapid decrease in pressure. The work of the heart muscle improves, the risk of developing cardiovascular diseases decreases. According to reviews of cardiologists and patients, treatment improves well-being on the first day, if you take drugs according to the instructions.
Characteristics of Amlodipine
The product contains amlodipine besyat in the amount of 6.9 mg or 13.8 mg (5 mg or 10 mg of amlodipine). Amlodipine reduces pressure to normal levels by blocking calcium channels. It prevents the penetration of calcium into the cells, promotes the expansion of blood vessels. The drug improves the blood supply to the myocardium in angina. After taking the heart muscle to a lesser extent in need of oxygen and reduced total peripheral vascular resistance.
To stabilize the state at elevated pressure, they take both drugs Amlodipine and Lorista.
The drug reduces the pressure for 6-10 hours and prevents the adhesion of platelets. The effect lasts up to 24 hours. The effect depends on the dosage taken. Admission does not increase the pulse rate. The tool can be taken with diabetes, asthma or gout. After ingestion, the active components are well absorbed and distributed in the tissues of the body. The half-life is 2 days. Excreted by the kidneys and through the intestines. In patients with liver failure with prolonged use accumulates in the body.
How does Lorista
The drug contains losartan potassium in the amount of 12.5 mg, 25 mg, 50 mg and 100 mg. The active component causes blocking of the angiotensin 2 receptor subtype AT1. Does not inhibit angiotensin-converting enzyme. Promotes the excretion of uric acid, prevents the release of aldosterone. After taking, the work of the heart muscle improves, the concentration of norepinephrine in the blood decreases, the pressure normalizes.
The effect occurs within 5-6 hours. The tool has no effect on cholesterol and triglycerides, glucose. Quickly absorbed and binds to albumin. Removal of metabolites through the intestines and kidneys during the day. With abnormal liver function, the concentration of the active substance in the blood increases.
The combined effect of Amlodipine and Loristy
Joint therapy helps to normalize blood pressure and improve the cardiovascular system. After taking it in combination, the vessels are dilated, the risk of a repeated increase in pressure is reduced, blood circulation is improved. The pressure decreases within 6 hours and the effect lasts up to 24 hours.
Comprehensive treatment can reduce the risk of developing pathologies of the heart or blood vessels.
Indications for simultaneous use
It is recommended to take in combination with arterial hypertension. The treatment will quickly reduce the pressure and improve the overall well-being of the patient.
Contraindications to Amlodipine and Lorista
Taking Amlodipine and Lorista at the same time for hypertension is contraindicated in such cases as:
- hypersensitivity to the components of drugs;
- liver or kidney dysfunction;
- chronic course of obstructive hypertrophic cardiomyopathy;
- unstable hemodynamics in the post-infarction period;
- severe inflammatory diseases in urology;
- concomitant use of aliskiren-containing drugs;
- lactase enzyme deficiency;
- violation of the breakdown of galactose and glucose;
- dry cough;
- varicose veins.
In childhood and if necessary hemodialysis is not recommended to begin treatment. Patients with ischemia, narrowed lumen of the renal arteries, cerebrovascular diseases, dehydration and low blood pressure should receive a specialist before admission. If you are prone to angioedema, treatment should not begin.
How to take Amlodipine and Lorista
The daily dose for hypertension is 25 mg Loristy and 5 mg Amlodipine. Tablets washed down with the required amount of liquid. The dosage is increased to 100 mg + 10 mg or 50 mg + 5 mg in the absence of effect. Lorist need to take in the amount of 12.5 mg or 25 mg, if there is an abnormal liver function.
In some cases, side effects may occur after administration, such as:
- emetic urges;
- allergic reactions in the form of urticaria, skin rash;
- abnormal liver function;
- kidney failure;
- increased concentration of urea, potassium, or creatinine;
- swelling of the legs;
- facial flushing;
- muscle pain;
- weight loss;
- abdominal pain;
In the presence of allergic reactions it is necessary to refuse to take medication. Symptoms disappear after stopping treatment.
Opinion of doctors
Oksana Robertovna, cardiologist
Both drugs are taken in combination with hypertension, including in comparison with other diseases of the cardiovascular system. Amlodipine relieves vasospasm and improves blood flow to the heart. Lorista prevents the increase in pressure and normalizes the activity of the heart. During treatment with antihypertensive drugs, tachycardia does not occur. It is possible to reduce the pressure while lying and sitting. It is necessary to take the instructions to prevent the occurrence of unwanted reactions. In old age, the doctor must select the appropriate dosage.
George, 39 years
The pill was taken with arterial and renal hypertension. The pressure drops to normal values within 2-4 hours after the first dose. The treatment is well tolerated. On the first day I was worried about dizziness, but then my condition improved. During treatment, you must abandon the diet. Meals should be complete.