Scientists have discovered a link between poor sleep and difficult soft tissue regeneration in type 2 diabetes. These data open up new perspectives in the treatment of diabetic foot and other tissue damage.
The formation of poorly healing ulcers at the wound site is one of the complications of diabetes. Legs are often subject to various injuries. Small lesions on the feet can turn into serious ulcers, which can lead to the development of gangrene and amputation.
Recently, the international medical journal SLEEP, devoted to the quality of sleep and circadian rhythms of the body, published the results of a study on the effect of intermittent sleep on the regeneration of body tissues. Scientists compared the condition of obese mice with type 2 diabetes and healthy animals.
34 mice under anesthesia were made small incisions on the back. Then the researchers measured the time during which these wounds would heal, dividing the mice into two groups. The first group of rodents had a sound healthy sleep, and the second group was forced to wake up several times during the night.
Intermittent sleep caused a significant slowdown in wound healing in diabetic mice. Non-falling animals took about 13 days for 50% healing of injuries, and for those that slept without interference, only 10.
Mice with normal weight and without diabetes showed the same results in less than a week, and a full recovery occurred after 14 days.
Scientists explain this by saying that Type 2 diabetes causes problems with blood circulation and damage to nerve endings. These complications increase the likelihood of wound infection.
Sleep quality also affects the immune system and complicates the healing process.therefore, sleep is crucial for the body’s immune response to damage and illness. It is known, for example, that people who regularly fall out of sleep are more susceptible to colds.
A combination of poor sleep and type 2 diabetes exposes people to an increased risk of developing diabetic foot. In order to reduce these risks, it is necessary to normalize the night's rest, if you need to see a specialist, if necessary, and to regularly examine the condition of the legs yourself.
You may find our article useful on how to care for your skin, especially your feet, in diabetes.