The drug Kreazim is indicated for replenishing protease deficiency, lipase and amylase, improving the digestive process, and the complete absorption of nutrients by the small intestine. The unique dosage form helps to prevent a decrease in the activity of pancreatic enzymes caused by their inactivation of gastric juice.
The capsules of the preparation are yellow, cylindrical in shape, contain fine beige-brown granules (dosage 10,000) or opaque capsules of red color with a black lid (dosage 20,000) inside.
Granules means are characterized by increased resistance to acid, evenly mixed with the contents of the stomach, then penetrate into the duodenum. Soon there is a rapid release, the activation of the active substances is triggered in a neutral or weakly acidic medium, where the granules disintegrate.
The price of the drug varies between 200-450 rubles. There are cheap Russian and imported analogues of tablets: Mezim, Pancreatin, Pancreatin Forte. The more expensive analogues include tablets: Creon, Festal, Hermital.
Instructions for use of the drug
Kreazim is indicated for the treatment of exocrine pancreatic insufficiency, chronic pancreatitis, cystic fibrosis, the elimination of errors in nutrition, the growth of pathogenic microflora in the small intestine. The drug is taken with obstruction of the common bile and pancreatic ducts, malignant and benign tumors in the body, for symptomatic treatment of disorders of the digestive process after gastric resection, biliary obstruction, pregastrostasis, cholecystectomy, liver cirrhosis, diseases of the terminal small intestine.
The capsule must be swallowed whole, drink a sufficient amount of liquid. The dosage is selected individually, taking into account the severity of pancreatic insufficiency, the diet of the patient.
It is standardly shown to take one-third or one-half of a single dose before a meal, the rest is consumed with food. The initial dose of funds - 10000-20000 IU of lipase. When there is a need to reduce steatorrhea, to maintain the normal state of health of a person, the doctor decides to increase the amount of funds. In this case, along with the main meal you should drink 20000-70000ED lipase, during a snack - 50000-20000 IU.
Treatment of cystic fibrosis depends on the indicators:
- the age and weight of the patient;
- control results.
A maximum of 2400 U is allowed per day.
If a person has difficulty swallowing, it is recommended to open the capsules, add the contents to liquid dishes that do not require chewing. The resulting mixture is taken immediately, it can not be stored.
The duration of treatment varies from a couple of days to several months, when the violations are caused by errors in the diet. If you need regular replacement therapy, you will need to take Creazim tablets for a couple of years.
If the patient has taken too much of the drug, the development of hyperuricuria (an increase in the concentration of uric acid) and hyperuricemia (lactic acid diathesis) are not excluded.
Such symptoms are significant, it is shown discontinuation of pills, the duty of the doctor to change the treatment regimen, to prescribe the necessary similar to the effect of the drug.
Features of the application, unwanted body reactions
The safety of the use of Kreazim 10000 and Kreazim 20000 during pregnancy, during the breastfeeding period, has not yet been studied. For this reason, you should abandon the drug, with the exception of a case where the intended effect of therapy is several times greater than the potential harm to the expectant mother and fetus.
It is necessary to consider the side reactions of capsules, despite the fact that they are observed only in 1% of cases. On the part of the digestive system, the patient rarely suffers from constipation, nausea, diarrhea, heaviness, discomfort in the abdominal cavity.
When a patient is already taking any medications, he should inform his doctor, as Kreasim is able to interact with some of them. For example, there is a decrease in iron absorption, which is harmful, requires additional prescription drugs.
The application guide indicates that enzymes are strictly prohibited in such cases:
- acute pancreatitis;
- exacerbation of chronic pancreatitis;
To exclude colon lesions, it is recommended to control all unusual symptoms, changes in the abdominal cavity, especially when receiving higher dosages of medication (over 10,000 IU per day).
On the part of the immune system, bronchospasms and oversensitivity reactions are observed. From the subcutaneous tissue and skin are not excluded allergic reactions of varying severity, hyperemia, itching, urticaria, rash. Common disorders include weakness in the body.
Treatment of the pancreas involves the use of a sufficient amount of fluid, otherwise there is dehydration, which aggravates the course of the disease.
You must comply with the storage conditions of the tool, you can not use the tablets after the expiration date indicated on the package.
Analogs of Kreasim
The drug Mezim is one of the most popular analogues of Kreasim, for adults and children it is given 1-2 tablets each, they are taken with food without chewing, drinking plenty of pure water. The duration of treatment is determined in each case, the child and the adult must take a different amount of money.
Taking increased dosage of medication may develop hyperuricemia, hyperuricuricuria, the treatment of a pathological condition should be symptomatic.
On the part of the patient's immune system, sneezing, skin rashes, bronchospasms, itching, hot flushes, angioedema, tearing, tachycardia, weakness and urticaria occur.
On the part of the digestive system arise:
- discomfort in the abdominal cavity;
- intestinal obstruction;
The presence of Azorubine varnish in the composition of Mezim causes allergic reactions. As the reviews show, the tablets do an excellent job with their task, side reactions are rarely given. Its use is justified in case of intolerance to other enzyme preparations.
Festal tablets are recommended in the period of recovery or for the expansion of the diet, if there is symptomatology of intestinal obstruction during pancreatitis, it is required to take into account the probability of intestinal strictures. It is shown to control any unusual signs. To prevent the formation of uric acid substances by controlling the concentration of uric acid.
The product contains active substances that can have a bad effect on the condition of the intestinal mucosa, stomach, therefore it is recommended to use it without chewing. Since tablets contain glucose and sucrose, patients with pancreatitis and diabetes need to take this into account.
How to treat pancreatitis is described in the video in this article.